The rule could be anything, as funny or as serious as you want. The universe will progress in a similar way that it has up until this point, unless your changed rule prevented it from doing so.
Some examples might be:
- The invention of currency is not allowed.
- Iron is slightly less stable.
- The Ancient Greeks are able to cultivate Silphium, which does not go extinct now.
George Lucas does‘t mess with his movies
Karma is real.
I will rmov thy lttr
Everything the same, but healing fantasies improve your mental health.
… Too meta?
Less power/increased liability for corporations.