It is a harrowing proposition: that in trying to control drug prices for 67 million Medicare patients now, we might inadvertently prevent the development of future drugs that could save lives. Implied, if not stated outright, is that we’re putting a cure for cancer or Alzheimer’s or some other intractable disease in jeopardy.

But we have good reasons to believe that the current policy won’t have such a trade-off any time soon. For one, pharma is hugely profitable, and these negotiated prices, while potentially chipping away at profit margins, should hardly entirely dampen the incentive to innovate, according to a couple of key studies of the industry. Two, if we are worried about future innovation, we should be focused on making it cheaper to develop drugs – and this is actually one area where AI is showing promise. By identifying the best candidates for possible treatments early in the research process, we could speed up development and continue to reduce costs — without losing out on tomorrow’s breakthroughs. …

100 points

FTFY…

Big Pharma claims lower prices will mean giving up miracle medications executive pay and bonuses.

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37 points

Haha no they meant what they said.

They’re not giving up their pay/bonuses.

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25 points
*

The correct answer is neither.

Miracle drugs are almost exclusively funded, or heavily subsidized, by the public sector. Typically through NIH grants, or other public funding mechanisms through the University system.

R&D budgets for a big pharma go to things like reformulating existing brand name drugs, to prevent them going generic as they are supposed to under current law. Or other high return, reduced effort, drugs i.e. new dick pills, narcotics, etc.

Executive pay and bonuses are not going anywhere, no matter what happens with these drug prices. They will cut their company to the bone, and then collude with private equity to take them private and gut it, before they ever considered cutting down their bonuses or stock options.

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13 points

I benefit from an orphan drug, and the R&D was most definitely subsidised by the public purse.

My insurance pays a few grand a month for it.

The mfg coupon covers most of the rest, minus a copay.

This is the second iteration of the original drug. The first hasn’t meaningfully fallen in price and only the original company can manufacture and distribute the generic even under the name of competitors.

There was no breakthrough in the second iteration, and the logic to solve the “problem” they solved was straightforward. So now I pay more, for an anecdotally less effective version that addresses a risk irrelevant to me but present in the original.

There is yet a third iteration on the way.

Shock revelations:

  • pharma companies are greedy and will double dip against both government subsidies and patients/insurance at every opportunity.
  • XX Pharma didn’t pay for the original R&D, my gov did.
  • if one replaces Na with a/several similar elements, one still ends up with a salt, often resulting in a drug variant that “doesn’t affect blood pressure” and offers no other real benefits, nor risks.
  • Clinical trials for said alternative salt are broadly leas expensive than for the original. That does not result in lower prices.

Nationalise pharma research, if not the manufacturers.

Also, generics are often manufactured in countries with, shall we say, fewer controls and regulations. Know who makes those pills and where. If you can’t stomach the FDA reports on that manufacturer, find a pharmacy who will sell you something else…

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11 points

This is correct. We pay for R&D, they keep all the profits.

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60 points

Seems like a good reason to nationalize the industry.

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10 points

It pretty much already is. All major drug discoveries this century received at least as much public funding as private.

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13 points

And despite helping to foot the bill no money ends up going back to the public.

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6 points

And public ownership of patents for drugs discovered by public institutions is explicitly forbidden by law.

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31 points

Assuming lower prices were mandated in the future, what is their alternative? Develop zero new medications and subsist on the current drugs they offer with soon to expire patents? I doubt their competitors will be sitting idly by waiting for their eventual demise. Their argument is so superficial.

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12 points

I doubt their competitors will be sitting idly by waiting for their eventual demise

That’s why you do M&As with your profits until there aren’t any competitors left

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29 points

Aren’t most of the RND costs paid for through government grants and donations…

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6 points

shush! ^the ^peasants ^don’t ^need ^to ^know ^that!

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25 points

For one, pharma is hugely profitable

This is just like Uber and Lyft threatening to pull out of markets when the taxes go up a bit. The horror, they’ll have slightly shittier margins and can’t survive with slightly less profit

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