Not too long ago, regulations on CBD changed in Germany leading to a plethora of products containing it. As someone who occasionally needs pain medication, I tried some of the products to avoid regular pain killers (ibu). Especially on days with lighter pain, I wished for an alternative to the sledgehammer meds. But I was left standing in the rain. I didn’t feel any effect. That’s why I would love to hear from your experiments and experience.
I’m having trouble finding it, but I ran across a study a few months ago whose results pointed to greater pain relief gains when CBD was consumed with THC, and that both substances alone do less to “relieve” pain.
I wouldn’t say it helps relieve pain as much as it lets you be distracted from pain.
Also, personally, when I have used CBD on it’s own, it never did anything for me at all. It only ever worked in combination with THC.
Finally, people taking other medications need to be careful about taking CBD.
The vast majority of medications are broken down by enzyme CYP3A4, an enzyme that CBD inhibits.
I am taking a life-saving/life-altering medication to manage a severe disease. It is handled in my body by CYP3A4. Meaning I can really fuck up my medication dosage by taking CBD on its own, because it will inhibit the ability of CYP3A4 to ingest the drug.
User pizza_rolls@kbin.social helpfully pointed out that grapefruit inhibits CYP3A4 as well, so if you’re not supposed to eat grapefruit, you should probably also avoid CBD. I hadn’t even made that connection myself, very astute, pizza_rolls!
You can’t think about what you feel; you have to think about what you don’t feel. What’s gone or lessened - anxiety, irritability, general discomfort, insomnia, etc.? Also, you have to be careful where you get it. For oils i like Lazarus naturals and Hoku Seed Co. Not sure if either so outside the US. It may take a bit for youto get max benefit from it - almost the inverse of thc tolerance.
Thank you! As a human, I’m excellent in leaving behind what bugs me in an unpleasant way until it hurts on a level I cannot ignore.
The thing with THC tolerance is also interesting. Does a CBD/THC mixture remain equally effective of the percepted effects of both constituents have mirrored tolerance/effect characteristics?
the problem is the legality of other cannibinoids where you live …
- from the states in the US where cannabis has been legalized – neither CBD nor THC will show their full effects in isolation, they each help to augment the other – so even something like a tiny amount of THC added to CBD (ex. 20:1 CBD to THC) will drastically enhance the CBD effects
- there are two primary (and a lot of secondary) pain systems within the body – one of them responds better to opioids, the other responds better to
cannibinoidscannabinoids – everyone’s different and responds differently so it requires a knowledgeable medical professional who hasn’t bought into US’s “reefer madness” propaganda that’s been foisted off onto the rest of the world
Thank you for your balanced thoughts! Well your first point kinda might be an issue. I guess I haven’t dived deep enough into this topic to answer whether these mixtures are legally available here. Speaking of it: can you (or someone you know 😉) feel any psychedelic effect of the THC with a 20:1 ratio?
I tried to convince trained professionals twice to go the mentioned route with me. Instead, the looked for me as if I asked for a roofie on the house. So that is another issue…
Chronic migraine sufferer here. Like 25+ days a MONTH, over 5 on the pain scale, plus all the other fun symptoms.
I had tried literally every other drug on the market for migraine, even some off label, except Botox. The newest class of migraine drugs wasn’t on the market yet. History tells me I likely will not do well with Botox, so as a last ditch effort, before trying it, I decided to experiment with weed again.
Life changing is an understatement. Went from most of the month, where I felt like I was slowly dying, to having MAYBE 2 relatively mild migraines per YEAR.
Certain strains work better for me as an abortive, than others, but just having it in my system daily gave me my life back. It doesn’t seem to matter whether is a 1:1 (CBD:THC) or just a regular old mostly THC strain, it just works for me.
Honestly, I don’t even need to get stoned for it to help. Just a small puff off the vape, once a day, and I’m good to go. I haven’t bothered to try playing with the not thc stuff.
The rare instance a migraine starts, at least weed is an incredibly predictable thing. A migraine can range from “eh I can power through” to “hmmm Half the vision in my right eye is gone”. I’ll take being stoned lol.
My wife has chronic neuropathic pain, and the CBD gummies seem to help her sleep. They don’t seem to overtly reduce the pain, but maybe make her less anxious about it.
