The polyfill.js is a popular open source library to support older browsers. 100K+ sites embed it using the cdn.polyfill.io domain. Notable users are JSTOR, Intuit and World Economic Forum. However, in February this year, a Chinese company bought the domain and the Github account. Since then, this domain was caught injecting malware on mobile devices via any site that embeds cdn.polyfill.io. Any complaints were quickly removed (archive here) from the Github repository.
In my experience, first-party JavaScript is more likely to be updated so rarely that bugs and exploits are more likely than supply chain attacks. If I heard about NPM getting attacked as often as I hear about CDNs getting attacked, I’d be more concerned.