I feel like I’ve heard that clearing the tangles really doesn’t affect the trajectory of the disease?
If mice ever become the dominant species, they’re going to start off so overpowered with advancements in medical treatments.
I’m convinced that the Alzheimer’s field is one of the areas of research that will be looked back upon with disillusionment.
Tau tangles and beta plaques have been fiercely and dogmatically pursued as causes and therapeutic targets of Alzheimer’s disease. However, it is becoming increasingly clear that these aggregations are likely a consequence of the disease that does not necessarily present an avenue for therapy. I.e. the harmful part of the disease probably acts upstream of or in parallel to the accumulation of the tau and beta aggregations
All because Sylvain Lesné and team published a fraudulent research paper in 2006. The field has possibly lost a decade of time and money.
Well, I’m certainly glad there a nasal spray that deals with the toxic mice tangles in my nose.
