my new psychiatrist gradually took me off of ritalin+venlafaxin and introduced bupropion, first 150mg while cutting the venlafaxin dosage in half, and now 300mg of bup alone, completely removing venlafaxin

it’s been 4 days i think since this last update and it’s been fucking rough. i’m not sure if it’s just the venlafaxin withdrawal or if the bupropion is contributing to it, but i feel like shit, i’m getting constant brain zaps unless i remain completely still with as little stimulation as possible, been having nightmares every single day, am extremely irritable and im not even sure the bupropion is even helping at all

is anyone else under the same treatment? it feels like a fringe/experimental treatment, but id like to confirm this from other adhders

thanks

edit: thank you so much for all the answers! they helped me to calm down and reassured me a bit. the symptoms are starting to wear off, so that also halped.

very late update: the venlafaxin withdrawal waned off and now i’m feeling so much better than before. this is working way better than ritalin

9 points

Not what you asked and I don’t take bupropion, but I did come off of venlafaxine, and it was a horrorshow of brain zaps and nightmares until I went onto fluoxetine.

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2 points

i knew venlafaxin withdrawals were nasty, but i didn’t know they could last so long. i thought id be fine after 2-3 days

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2 points

my Dr said to expect a couple weeks when I go off it, if I ever do. and supposedly the all the way off is worse than just going down

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1 point

i wish i was warned like that

it frustrates me so much. the doctor that introduced me to venlafaxin never warned me about the withdrawal symptoms, even though i showed concerns about that, and the current doctor never warned me that they would linger for so long

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13 points
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I have been on both of those and I don’t think you’ll notice the bupropion helping until you’re out of the withdrawing stage. Venlafaxine is a really wicked one to quit, I’m a bit surprised your doctor didn’t do a longer taper off schedule.

For what it’s worth, I really loved buproprion, and it’s done wonders for my bff who also has adhd.

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2 points

my venlafaxin dose was originally 75mg, so he planned to reduce it to 37,5mg for a month then take if off completely. reducing to 37,5 was fine so i thought taking it off would be too ig

fwiw not feeling that annoying ritalin anxiety anymore last month did indeed feel pretty good. your comment gave me a little bit of hope, so ty

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When I was put on bupropion it made me dissociative, but I’m also bipolar which may have played a role. My psych prescribed it bc she didn’t want to put me on a classical stimulant specifically because I’m bipolar. I ended up on Ritalin though, which didn’t have significant adverse effects

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3 points

Bupropion is rough. I took it for nearly a decade for depression. Headaches, shakes, and fuzzy memory. It didn’t help my ADHD (then-undiagnosed), but it did wonders for making me feel less physically exhausted during periods of depression.

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3 points

Yeah as the others have written, the withdrawal off venlafaxin is rough. If I could change one thing in my life it would be to taper it off for half a year or more. I took it out too quickly I think and dealt with the symptoms of withdrawal for months.

Bupropion for me was the first antidepressants that seemed to really work while still making me feel human. Lots of bad stuff didn’t happen. Now I’m slowly getting rid of it. It’s gonna take me months this time… Good luck with it. Everyone’s experience is gonna be different.

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2 points

My doctor cut my dose way too fast as well and it definitely sucked but I adjusted after a couple weeks. She did raise my bupropion at the same time though.

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