It just seems like it would be a really cool thing to have gills and be able to populate the oceans in the same way we populate the land. We could have houses and shops and vehicles, andgo on walks/swims and just kind of live underwater.

Start a whole new second species of human here on earth maybe, Who knows?

6 points
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Yes, but not very good ones, probably. We’re endotherms (hot blooded), and as a result we burn like 3 times as much oxygen as a similarly-sized shark. You’d need a lot of gills.

The rest of our body is also not very well suited to being underwater long-term. If you’re adding gills you might as well change our silhouette, eyes, hair and skin as well, but you might not look very human afterwards. Maybe you could manage something merperson-ish, with an extra-flexible neck for looking towards where you swim and gills all along the tail? Sanitation would also be a bit of a nightmare, because if there’s a sewage leak you get to breathe it.

The other option is just to get really good at diving conventionally, maybe enhance ourselves to make that easier, and build dry “indoor” spaces underwater. The technology to do it at a basic level isn’t new, but there just hasn’t been much interest in living that way yet.

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8 points

Changing the color of your eye take so much changes that’s impossible todo it, gills is going to need so much changes, and we don’t even know what most of our genes do

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3 points

Give it a hundred years or so

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12 points

Yes, but being able to change genetic code does not mean being able to design entire organs and pop 'em in there during fetal development. That would be very challenging.

Gene editing has the most positive potential when it comes to things like curing/eradicating genetic diseases, doing microbiological research, or engineering metabolic products in microorgsnisms.

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3 points

Single loci genetic diseases. Those with numerous genes contributing will me even more difficult.

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32 points
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In short, we could, but the cost would be incredible.

All vertebrates are animals that develop from a series of segments, with a vertebra at the core. In our time from eel-like fish, we’ve specialised these segments so, for example, we have ribs on the vertebra corresponding to the rib cage.

To support arms and legs, specific vertebra have become highly specialised in the form of hips and shoulders.

Gills are composed of a series of gill arches, one on each vertebra in the neck area. These structures have (in eels) a lot of blood vessels to carry the blood that needs reoxygenation.

An interesting thing happened as the eel-like creatures differentiated, evolved jaws and ultimately ended up as mammals and humans: nature co-opted the specific vertebra that had these gill features and turned them into jaws and ears and a variety of other features in the head and neck. For example the tiny bones in your ear were once fish jawbones which were previously one (or more) gill arches.

The stupendously complex anatomy in this area comes from all the short-term ‘decisions’ evolution took to make all the magnificent creatures that inhabit the earth.

For example the nerve that connects the brain to the larynx (the recurrent laryngeal nerve) emerges from a vertebra high up in the neck, decends down under the aorta in the chest and then back up into the neck to the larynx. In the giraffe, the nerve is many meters long, even as it’s direct path could be a few centimeters. The reason is that the heart used to be close to the gills in fish and sharks. As the heart moved in land animals, the nerve was caught in a loop around the critical aorta and it was ‘pulled’ along for the evolutionary ride.

So, in order to turn your gills back on, you need to unprogram 450m years of evolution of the structures you call your head, face and neck.

I’d recommend ‘Your inner fish’ by Shubin - it’s a wonderful read and explains this in far more detail that I can manage.

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2 points

Fuck it, let’s do it. Super Mario Bros deevolve me

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10 points

Fascinating.

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7 points

If you like this, this goes under the moniker ‘evo/dev’ - evolution of the ‘development’ of the organism. A lot of genes don’t code for proteins that ‘do’ something in the body, like haemoglobin or fingernails - they code proteins that tell the body how to develop from a single cell. Many are active for a short window in development. Some are active in a single location, like at the thumb end of the limb bud, and tell the cells where to become a finger, thumb or palm bone. Some work across vastly different animal classes - the ‘build an eye here’ gene works in humans and flies and everything in-between.

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6 points

So there isn’t a way to “add” a feature on top of the existing organism’s physical system? We have to lose ribs to get gills? That kinda sucks.

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2 points

Sure. I take lungs now, give you gills next week.

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