A lot of people believe we can, yes. However there are a few technologies that still need to be developed, such as a reliable power source that can work during a long lunar night

• solar won’t work, because night is too long
• RTGs can’t scale up enough to power a base
• Fission reactors as we have them so far generally rely on a liquid coolant and a lot of maintenance attention
• Even assuming we’ll be able to mine ice, it’s not something we can rely on to power a base, and we haven’t yet figured out how

So, if we can develop a small fission reactor that never needs any attention, can work in lower gravity, no atmosphere, huge range of temperatures , and doesn’t have anything that can leak, boil, or freeze, that would be perfect