In the United States, I’d probably name Oregon City, the famous end of the Oregon Trail and the first city founded west of the Rocky Mountains during the pioneer era. Its population is only 37,000.
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Pronounced kæro (K air o)
Comically, in Latin the æ would be pronounced with a sound like “ai” in “aisle,” so kæro would be pretty much the same as how you would expect to say Cairo.
(Fun fact, in Latin “Caesar” is pronounced very similarly to “Kaiser,” and is where the word “Kaiser” comes from.)
