I expect that will happen. When Bernie campaign failed, it was an eye opener for a lot of people that the game is rigged and radicalized them further to the left.
If the smug gaslighting from the Adults in the Room about the reasons for Sanders’ two campaigns failing didn’t radicalize someone, I thought nothing ever could. But this election failure might.
Also worth noting that the material conditions have declined significantly since Sanders ran. A lot more people are now seeing their own living standards declining, making it easier for them to realize the problems in the system.
The DNC will probably still hang on as a permanent minority party blocking the formation of a viable left party for like 20+ years before anything could replace it. As long as they have donors to pay for ads the party leaders get a cut of, all the existing financial incentives are there for the DNC to just lose a half dozen presidential cycles and not really care because Neera Tanden and Donna Brazil can sill cash a check.