The researchers found sweeping changes in overall brain neuroanatomy which unfolded week by week during the pregnancy.
Inside Chrastil’s brain, grey matter volume, cortical thickness, white matter microstructure, and ventricle volume all changed.
The changes were all over the brain too — “over 80% of my brain regions showed reductions in grey matter volume,” Chrastil said.
Neuroanatomical changes observed over the course of a human pregnancy. Published by Pritschet, L., Taylor, C.M., Cossio, D. et al. in Nature Neuroscience (September 2024). https://doi.org/10.1038/s41593-024-01741-0
this is the first study to consistently map brain changes during pregnancy, write the study authors in their paper.
“It’s 2024 and this is the first glimpse we have of this fascinating neurological transition. There is so much about the neurobiology of pregnancy we don’t understand yet. It’s a biproduct of the fact that biosciences have historically ignored women’s health,” said Jacobs.
I knew that there were fundamental neurological changes that occurred during pregnancy, but had no idea that there hadn’t been a comprehensive brain mapping study done yet. There is a surprising amount of sexism in academia.
