For example, for me, I would *love* a new Populous game based from what was done in Populous 3. That, and a new SimCity based on SimCity 4!
Came to say inFamous, but specifically picking up after the evil ending in 2. The way that frames it could allow for character customization, and maybe even getting to choose your powerset.
It could even have multiplayer elements if that’s where they wanted to go with it. Not sure how well PvP would work out, but co-op missions could be fun. But, it could work just fine without any of that